Fans excited to witness Winfrey’s announcement (AP)

A studio audience lines up outside Harpo Studios for a live broadcast of The Oprah Winfrey Show Friday, Nov. 20, 2009 in Chicago. Winfrey is expected to officially announce during the live broadcast Friday, that her powerhouse daytime television show will end its 25-season run in 2011.  (AP Photo/Charles Rex Arbogast)AP - Fans who will be in the audience at "The Oprah Winfrey Show" say they're excited to hear the media mogul talk about her plans for the future.